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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
Fresno, CA
May 30, 2025
 · 
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A myRAteam Member

I have experienced many of these same symptoms, never thought of the prednisone. I thought it was a combo of all the meds I'm taking. I see my rheumatologist & neurologist in 2 weeks, will definitely mention this as to them. Do grateful for this group.

June 8, 2025
A myRAteam Member

During a really bad flareup like I'm experiencing right now I always go on Prednisone. I have been on it for the past 3 weeks and will be on it for at least another 3 weeks, I'll be seeing my Rheumy on Tuesday so well see if I will need it longer. Haven't needed to be on it more than 3 months yet. It's truly a miracle drug but the side effects can make it seem like a nightmare drug as well. For me it starts to ease the pain, stiffness, and swelling very quickly within the first 24 hours but then starts making me feel quite ragey (angry) and causes a total personality change away from who I am, makes me anxious causing panic attacks, I get upset at the tiniest ridiculous things and have no patience or tolerance, makes me sweat, causes my hunger to increase, messes with my concentration, increases my OCD, and gives me insomnia. It is usually not quite this bad, but I started on 30mg instead of the normal 20 mg and am slowly tapering down a pill every 7 days. I don't think I could live without it either though because I wouldn't be able to function at all without it during a flareup. Definitely a love/hate drug for me.

June 6, 2025
A myRAteam Member

I've been on prednisone for a while. Each time the doctor wean me off, the RA symptoms return worse than b4. So right now, I take prednisone, & methotrexate. I hope the pred will be reduced to every other day soon. I call it a miracle pill because it works for me. But for a little pill, it is mighty powerful and dangerous if not taken properly.

June 1, 2025
myRAteam

Prednisone, a corticosteroid medication, helps reduce inflammation and regulates the immune system in people with RA. It's often prescribed alongside DMARDs as a temporary solution to manage joint pain and swelling while waiting for longer-term treatments to take effect. As for timing, most people begin feeling the effects Show Full Answer

Prednisone, a corticosteroid medication, helps reduce inflammation and regulates the immune system in people with RA. It's often prescribed alongside DMARDs as a temporary solution to manage joint pain and swelling while waiting for longer-term treatments to take effect. As for timing, most people begin feeling the effects of oral prednisone within 1-4 days, though some notice improvements in just a few hours. For best results, doctors typically recommend taking prednisone early in the morning, though some suggest taking it late at night to help prevent morning stiffness.

Important note: While prednisone can provide quick relief, it's not recommended for long-term use due to potential side effects like weight gain, osteoporosis, and changes in blood sugar and blood pressure.

May 30, 2025
A myRAteam Member

Hi Michelle, I have only taken 5 mg a day. It used to be very helpful for pain, stiffness, and such. I have been on it for so long, many years now. When I get seriously ill with flare I usually get an injection and that works wonders compared to the pills for me. I have heard that higher doses of prednisone can cause mood swings. I hope that you will feel better real soon., Bev

June 6, 2025

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