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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Infusions

A myRAteam Member asked a question 💭
Orlando, FL

I have been getting Simponi Aria infusions every 3 months for about a year. I do not feel it is helping as much as it should so my Rheumatologist sent a request for insurance to cover Cimzia (not sure of spelling) that is a shot once a month. Of course insurance has denied this. What medication to you use that you have seen good results from that doesn't have huge side effects. Also I took methotrexate but that also is not doing much good. So wondering what you are using that you actually see… read more

May 25, 2025 (edited)
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A myRAteam Member

We all react to these drugs differently , so trying is the only way.I know it is not fun, but you will get one that helps you!
I have been on so many over time years but some helped for quite a while. Now…my body only seems to allow Methotrexate now, and not sure it is doing much ,until I stop it!! I have had some heavy drugs that worked for over 3 years. There is hope ,and we should at least try I know it is scary, but we don’t seem to have other options!
I hope you all have a good day.
Nola

May 25, 2025
A myRAteam Member

I have tried hydroxychloroquine and sulfasalazine and they hurt my stomach.

May 25, 2025
myRAteam

When methotrexate hasn't been effective, there are several medication options to consider. Disease-modifying antirheumatic drugs (DMARDs) like leflunomide, hydroxychloroquine, and sulfasalazine work by treating the root cause of RA and reducing inflammation. While these medications can take 1-3 months to become effective Show Full Answer

When methotrexate hasn't been effective, there are several medication options to consider. Disease-modifying antirheumatic drugs (DMARDs) like leflunomide, hydroxychloroquine, and sulfasalazine work by treating the root cause of RA and reducing inflammation. While these medications can take 1-3 months to become effective, they may provide whole-body symptom relief over time. For more immediate symptom relief while waiting for DMARDs to take effect, NSAIDs like celecoxib, meloxicam, or other prescription NSAIDs can help manage pain and inflammation. Additionally, short-term use of glucocorticoids (corticosteroids) can quickly reduce swelling and pain during flares while transitioning to a new treatment plan.

It's important to note that all medications can have potential side effects, and what works best varies between individuals. Regular blood tests and close monitoring by your rheumatologist will help ensure the safety and effectiveness of any new treatment plan.

May 25, 2025

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