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It's important to know that methotrexate can take time to work effectively, even after a dose increase. The shooting pains you're experiencing could be from an active RA flare-up that's unrelated to the medication itself. Increased joint pain is not actually a known side effect of methotrexate. Rather than stopping your Show Full Answer

It's important to know that methotrexate can take time to work effectively, even after a dose increase. The shooting pains you're experiencing could be from an active RA flare-up that's unrelated to the medication itself. Increased joint pain is not actually a known side effect of methotrexate. Rather than stopping your medication, you should contact your rheumatologist about these symptoms. They may recommend additional temporary treatments to help manage your pain while the methotrexate takes effect, such as corticosteroids, anti-inflammatory medications, or using heating and cooling pads. Your doctor can also evaluate whether your current treatment plan needs further adjustment to better control your symptoms.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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