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I’m weaning off prednisone…taking 1 mg for second week. Still on Humira and plaquenil. I’m guessing I need to go back up on the prednisone unfortunately. Still on Humira and Plaquenil.

August 21, 2023
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Answer Summary

Members responded to someone asking about pain at the bottom of the leg where the foot bends while weaning off prednisone, with many... Read more

Members responded to someone asking about pain at the bottom of the leg where the foot bends while weaning off prednisone, with many confirming they experience similar ankle and foot pain related to rheumatoid arthritis, particularly when walking downstairs or downhill. Several members shared that ankle braces provided helpful support and pain relief, while others described challenges with biologics like Humira losing effectiveness over time and the frustration of needing steroids to manage inflammation despite their harmful side effects on bones, blood sugar, and digestive health. A recurring theme was the difficulty of balancing medication effectiveness with steroid dependence, with one member noting that their rheumatologist uses the ability to wean off steroids as a key indicator of whether a biologic is truly working.

A myRAteam Member

I'm on Humira and methylprednisolone because the Humira isn't working and I had the same problem. I'm waiting for a rituximab infusion but as for that pain, I had to take it easy for a week and it passed but now I'm afraid of walking too much because I don't want it to flare up again. My rheumatologist usually gauges if a medication is working by seeing if I can wean off the steroids (I know the short term and long term effects are absolutely awful, but I don't have much of a choice right now). Hope you feel better soon. You're not alone.

August 22, 2023
A myRAteam Member

Elyse be careful with prednisone it can cause your sugar to rise.

August 21, 2023
A myRAteam Member

Humira and Enbrel are for people with mild 🙄 😒 RA. I was on Enbrel and it only work for a short while. Then Remicade, Infliximab, now Rituximab so far it's working well.

August 21, 2023
A myRAteam Member

I don't have that problem. I will say I am on Humira too. It helped in the beginning, It is not as effective now. I don't know if the RA is worse or Humira just not right for me. I had the same thing happen when I was on Orencia. Both I was on for about 18 months. I wish you well

August 21, 2023
A myRAteam Member

I’m assuming it’s inflammation like I get on my knees, feet, fingers and toes. I wore an ankle brace to help improve support and decrease pain, especially when walking on stairs.

August 24, 2023

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