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I'm not advertising this - I'm just offering this information that maybe able to help you and your doctor find what's will work for you.

PrismRA works by showing if tumor necrosis factor-α inhibitor (TNFi) therapies, one of the most commonly prescribed RA medications, are less likely to work for you. The PrismRA result helps your doctor avoid prescribing this type of medication and instead, begin a medication that may be a better match for you.

Most of us often go through a process of trial… read more

June 3, 2023 (edited)
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Answer Summary

Members shared mixed feelings about PrismRA, a test designed to predict whether TNF inhibitor medications will work for rheumatoid arthritis,... Read more

Members shared mixed feelings about PrismRA, a test designed to predict whether TNF inhibitor medications will work for rheumatoid arthritis, with some expressing interest in anything that could shorten the frustrating trial-and-error process while others noted concerns about the company's potential conflicts of interest. Several members described their own lengthy diagnostic journeys, including years of testing different biologics like Enbrel, Humira, Cimzia, and Orencia, with some experiencing severe side effects or even developing cancer from medications that initially worked. A recurring theme was the emotional and physical toll of waiting months or years in pain to find effective treatment, paired with hope that advances in testing like PrismRA or Vectra DX could help patients and doctors make more informed decisions faster.

A myRAteam Member

Took me over 2 years to figure it out only to find out the drug that finally worked gave me cancer. So I'm being treated for cancer and a drug that also works with RA to put me in remission. So far after 2 treatments I'm doing well. Wish they could find something safe.

June 3, 2023 (edited)
A myRAteam Member

Has taken years for me did well on cortisone but couldn't stay on it. I'm now on embrel 2nd biologic I'm trying. Can feel a definite improvement. I take it with the methotrexate

June 3, 2023
A myRAteam Member

Nellie and Regina
Did the Vectra test help figure out the right medication to take?
I would say yes to a test that would shorten the time and sickness and new illnesses from trying each new med.

June 3, 2023
A myRAteam Member

Our RA doctor said NO to Prism since Pfizer has a vested interest. He is more than willing to do the Vectra DX test. Blood work next week. First Vectra DX says inflammation is way down (29). Yes, Cimzia can stop working. Will cross that bridge when we come to it.

June 3, 2023 (edited)
A myRAteam Member

It took me a while to find a medication that did not cause so many intolerable side effects. I dislike the trial-and-error process many of us go through to find a medication that works. We wait weeks in pain to see if the medication works. Then, we report our side effects to our Rheumatologist and move on to another medication that may or may not work. I feel with science/technology and medical advances we should have a better process of finding the right medication. For me it is a yes, I would request this Prism RA test.

June 3, 2023

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Cleveland, OH