Seems like this whole RA thing is trial and error 😕

I take Orencia however I have a cousin that lives back east that takes Simponi (one infusion per every 8 weeks) and 4 methotrexate tablets(once a week). She is 72 yrs young. Is able to work 4 full days per week at Walmart. She has done so well on this combination.. I saw her before Simponi and then after. My opinion is that she has done so well. I do believe that medicine is personal it may work well for you or may not be the best. I would study both meds. Cross match them with my R/A symptoms and then decide. Hope this helps.... I use wikipedia to study my meds and my symptoms.😊

I am just starting simponia aria infusions. I just gad my second one . I am taking hydroxy chloroquin and sulfasalzine . This second infusion has me feeling yuck, and low energy . Hooing its just from westher change

I hope you find a combination that works for you.

I am on same treatment. Started infusion times almost three months ago. Been on metho for over 20 years. No major side effects, but my severe disease not responding to infusion. See Dr. in August. May have to switch infusions. Best of luck. Praying