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Headache And First Does Of Methotrexate

A myRAteam Member asked a question 💭

Yesterday was my first does of methotrexate and today i have horrible headache. I have taken celebrex it has not helped. Wonderimg if okay to take migraine meds . What helps witb the headaches??

April 10, 2021
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A myRAteam Member

I can only imagine how you feel with your headaches.
Having been on 25 mL injectable of methotrexate once a week for 40 years, some things I have learned:
Celebrex is simply a nonsteroidal anti-inflammatory drug.
As with all our chronic disease treatments, WE are ALL different and respond differently. Methotrexate has been widely used for decades.
You do not want to take methotrexate with NSAIDs:
Advil
Aleve
Motrin
Ibuprofen
Naprosyn
Nuprin
You can take Tylenol if needed.
Before you do anything, no surprise here, make sure your healthcare provider is aware what you are taking with methotrexate! Methotrexate can be hard on your liver and we certainly don’t want additional drugs that compound that one!🥴
I believe you’re doing great!🌹
Gratitude for your coming here and looking for the support of all these wonderful people as we journey together finding our BEST PATHS forward!💪 Good job out of you!

April 11, 2021
A myRAteam Member

When I first started taking methotrexate I had a headache for several days. My doctor prescribed 3mg of folic acid per day. This requires a prescription, no more headaches!

April 14, 2021
A myRAteam Member

If you keep having headache with that medicine ask for something else

April 11, 2021
A myRAteam Member

I was OK with Methotrexate after the 4th dose. I found drinking lots of water helps the body and its side effects.

May 6, 2021
A myRAteam Member

Yippee for Tasha!🥳👏

April 16, 2021

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