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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

How Hard Is It Giving Yourself Methotrexate Shots? Anyone Gave A Bad Reaction?

A myRAteam Member asked a question 💭
Longview, WA

I took the oral twice and had severe stomach problems. Doctor says with the shot I won't have these problems, so I'm hoping she's right. I'm taking the folic acid also, as well as Hydroxychloroquin and Meloxicam. Anyone else have luck with these drugs?

September 15, 2020
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A myRAteam Member

The methotrexate injection are easy to give yourself and you start to develop a routine
The needle is so fine you don’t feel it
Wash hands, with alcohol wipes wipe the top of vial, I always give the needle an extra twist to make sure it’s on tight, withdraw amount of med,getting out any bubbles, while in sitting position I put one hand just above knee,one hand below hip, this whole outside area of thigh is your target area.cleanse spot, bunch of spot chosen with 2 fingers and with other hand at a slight angle take needle and like a dart aim for area, Stabilize needle with your 2 fingers that are holding skin,hold needle in place and inject With other hand and withdraw, doesn’t burn,avoid veins cause you’ll bruise. Always rotate sides each injection, right leg,next time left.way i remember cap on vial doing right cap off doing left
You can also use sites on abdomen
I do my injections in the bathroom after a shower sitting on the toilet with lid closed
You’ll be taught how to do the injections and you’ll be just fine
You got this!

September 16, 2020
A myRAteam Member

I’ve been taking methotrexate on and off for about 10 years. I have also found the injection to have less side affects than the tablets. The folic acid also helps with some of the symptoms of the methotrexate.

September 16, 2020
A myRAteam Member

I take methotrexate shots and folic acid, better then taking tablets

September 15, 2020
A myRAteam Member

I have no problem. In the UK I’m prescribed the pen form injection. It’s very easy.

June 19, 2023
A myRAteam Member

I was on injections of methotraxate which I gave myself. But have since been moved to another drug. My older sister has to have it by shot as she has a colostomy bag and she needs instant absorption. But she uses the new needle that is preloaded and looks and operates like an Epee pen. I don't know the spelling.

September 18, 2020

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