My rheumatologist wants to take me off of Methotrexate and put me on Leflunomide. I've never heard of this drug and I was wondering if anyone is familiar with it and whether or not it worked for you. Thank you in advance for any answers!
This was added to my pills several months after starting methotrexate and plaquenil. The methotrexate and plaquenil were not working. Took three of them the same time. It was the sickest time I was ever in my life. Drove my liver count up and I ended up with a brutal flu for a month. None of these drugs did anything for me and made me worst especially when I took all three but every one is different. I settled out with Cannabis oil and a keto type diet and have little to no pain and life is back to pretty much normal.
I was on this med for a short while but it did not help me at all. So I moved on to Humira which worked for about six months after which it did nothing and I was in severe pain all joints started hurting.
I was unable to walk. For the past three months I have been on weekly ENBREL injection and Celebrex which I take twice daily. This combination has decreased the joint swelling tremendously. I Now have more mobility and less joint pain.
My pharmacist wife says while both Methotrexate and Plaquenil are both DMARDS their mode of action is very different, so they are sometimes a common rheumatologist combo for folks who may perhaps need more relief than either one alone gives, and/or perhaps that their lab values may be higher than their rheumatologist may prefer to be on only one DMARD at a time. Of course, always follow the advice of your own doctor. As their are many RA meds and combos of meds doctors can choose from for any particular patient. Only your doctor can diagnose your unique situation and prescribe the best treatment plan. Asking questions of your rheumatologist is certainly fair and allowed to know the why of whatever treatment plan one is put on. Best wishes.