Answer Summary

Members shared their experiences with abnormal blood test results while taking methotrexate, with several describing elevated liver enzymes,... Read more

Members shared their experiences with abnormal blood test results while taking methotrexate, with several describing elevated liver enzymes, low white blood cell counts, and kidney function changes that required temporarily stopping the medication or adjusting dosages. Many members recounted the difficult trade-off between managing dangerous side effects and enduring severe arthritis pain without treatment, with some missing weeks of work during medication breaks and others cycling through multiple biologics without finding lasting relief. A recurring theme was the frustration of balancing the risks of organ damage against the debilitating pain of untreated disease, with strong encouragement to communicate openly with doctors about test results and explore alternative medications when necessary.