I am on Humira and was previously on Methotrexate and Plaquenil, but had to stop, because of bad GI symptoms. It seems none of the treatment is working and I have been feeling worse and worse. It's been 2 months on Humira. My rheumatologist says to try it for 1 more month.
Maybe you could do the injections for mtx and your GI problems may be alot better. That is the only way I can tolerate it. Good luck