What are the side effects of Plaquenil for someone with rheumatoid arthritis, and what should be considered with compensated liver cirrhosis?
Plaquenil (hydroxychloroquine) is a commonly prescribed DMARD for RA that works by calming the immune system to reduce joint pain and swelling. Most people tolerate it well, but it's Show Full Answer
What are the side effects of Plaquenil for someone with rheumatoid arthritis, and what should be considered with compensated liver cirrhosis?
Plaquenil (hydroxychloroquine) is a commonly prescribed DMARD for RA that works by calming the immune system to reduce joint pain and swelling. Most people tolerate it well, but it's worth knowing what to watch for.
Common side effects can include:
- Nausea, vomiting, and abdominal pain
- Diarrhea
- Dizziness and headaches
- Fatigue
- Rash, itchiness, or hair loss Rare but serious side effects include:
- Low blood cell counts
- Heart disorders
- Liver failure
- Visual disturbances or deafness
- Seizures
Given that liver cirrhosis is already a factor, the risk of liver-related side effects with Plaquenil is something to discuss carefully with a rheumatologist and liver specialist together. Regular monitoring of liver function would likely be especially important in this situation.
Eye health is also a key concern — an eye exam is recommended within the first year of starting Plaquenil, then every one to five years, as it can cause serious eye problems at high doses over time.
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