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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 20
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myRAteam

It sounds like the steroid injections are wearing off sooner than they used to — and that's actually a recognized pattern with long-term steroid use. A myRAteam member shared something very similar: "I've been getting cortisone injections in my knees every four months for about five years. They have been wearing off a Show Full Answer

It sounds like the steroid injections are wearing off sooner than they used to — and that's actually a recognized pattern with long-term steroid use. A myRAteam member shared something very similar: "I've been getting cortisone injections in my knees every four months for about five years. They have been wearing off a little sooner each time."

This "wearing-off effect" is common the longer steroid injections are used. It's really worth bringing this up with your doctor, as there are other treatment options that may provide longer-lasting relief, such as:

- DMARDs like methotrexate or sulfasalazine
- Biologic medications like etanercept (Enbrel) or infliximab (Remicade)
- NSAIDs for shorter-term pain relief
- Rehabilitation therapies like stretching, heat/ice therapy, or aerobic exercise

Long-term steroid use also carries risks worth discussing with your doctor, including effects on bone strength and other areas of health. A conversation with your rheumatologist about switching or adding treatments could make a real difference.

September 20

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Toledo, OH