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A myRAteam Member asked a question 💭
Alexis, NC

I were diagnosed with RA last month with knee pain morning stiffness crp <20 sed 24 ccp 14

September 4
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myRAteam

Can stem cell therapy help with RA, especially for someone recently diagnosed with knee pain and morning stiffness?

First off, a recent RA diagnosis can feel overwhelming, but it's great that you're already exploring options! Stem cell therapy is a promising area of research for RA, but it's not yet FDA-approved as a Show Full Answer

Can stem cell therapy help with RA, especially for someone recently diagnosed with knee pain and morning stiffness?

First off, a recent RA diagnosis can feel overwhelming, but it's great that you're already exploring options! Stem cell therapy is a promising area of research for RA, but it's not yet FDA-approved as a treatment.

The type of stem cells being studied most for RA are called mesenchymal stem cells (MSCs). They work by calming down the immune system, which may help reduce joint inflammation, pain, and stiffness. Early research results are encouraging:

- Lab studies show MSCs can suppress overactive immune cells in RA
- Animal studies showed improvement in bone erosion and joint inflammation
- Small human trials found reductions in pain and disease severity with no major side effects
- A 2022 clinical trial showed improved joint pain and swelling after one year

However, larger clinical trials are still needed to confirm these findings. There are some important cautions to keep in mind:

- Unproven stem cell therapies can carry serious risks, including infection
- The FDA recommends only using therapies that are FDA-approved or part of an official clinical trial
- Treatments offered outside the US may not be regulated or tested for safety

Since your diagnosis is very recent, talking with your rheumatologist about established treatments first, and asking about clinical trial eligibility, would be a really solid next step.

September 4

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