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A myRAteam Member asked a question 💭
Syracuse, NY
July 18
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Yes, RA and psoriatic arthritis (PsA) can definitely be confused with each other — and it's more common than you might think! Both conditions cause joint pain, stiffness, swelling, and fatigue, which makes telling them apart tricky.

Here are some key differences that help doctors distinguish between the two:

- Joint Show Full Answer

Yes, RA and psoriatic arthritis (PsA) can definitely be confused with each other — and it's more common than you might think! Both conditions cause joint pain, stiffness, swelling, and fatigue, which makes telling them apart tricky.

Here are some key differences that help doctors distinguish between the two:

- Joint patterns: RA tends to cause symmetrical joint pain (both knees, both wrists), while PsA is often asymmetric
- Location: RA more commonly affects wrists and finger joints closest to the hands, while PsA tends to affect joints near the nail bed and feet
- Skin symptoms: PsA is linked to psoriasis, which causes scaly skin patches — RA does not cause this
- Blood markers: About 80% of RA cases are seropositive (showing RF or anti-CCP antibodies), while most PsA cases are seronegative Seronegative RA (where blood markers are absent) can make the confusion even greater, since both seronegative RA and PsA lack those distinguishing antibodies.

Imaging, blood tests, and a thorough physical exam are all used together to help reach the right diagnosis. If there's ever any doubt about a diagnosis, it's always worth raising concerns with a rheumatologist.

July 18

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