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I have seropositive RA since 2021
Positive for Rhumatoid factor and and and ccp antibodies. Im currently 28 weeks pregnant today ☺️ but I had my son 12 years ago at 29 weeks that was due to preeclamsia and eclampsia. This time I have a higher than 1in3 of developing it again
I had a huge flare up 3 weeks ago in mt right hip and nearly hospitalised again because my crp was so high.
But I was told today by my Rhumatologist that the sulfasalazine i was switched to (safe in pregnancy) only has a… read more

June 1
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myRAteam

Congratulations on 28 weeks! 🎉 It's completely understandable to feel frustrated after pushing through that flare — especially when the medication simply wasn't doing enough for you. Hopefully this switch brings some real relief soon.

Cimzia is a TNF inhibitor (biologic), and the American College of Rheumatology considers Show Full Answer

Congratulations on 28 weeks! 🎉 It's completely understandable to feel frustrated after pushing through that flare — especially when the medication simply wasn't doing enough for you. Hopefully this switch brings some real relief soon.

Cimzia is a TNF inhibitor (biologic), and the American College of Rheumatology considers TNF inhibitors generally safe during pregnancy when needed to manage RA symptoms. It's actually one of the preferred biologics during pregnancy.

Some things worth knowing about Cimzia during pregnancy:

- It's considered lower-risk compared to some other biologics because it transfers minimally across the placenta
- Your rheumatologist may discuss whether to continue or adjust it in your third trimester to reduce infection risk in your baby
- Always keep your obstetric team in the loop given your history

Regarding timing, TNF inhibitors can take several weeks to show noticeable improvement — sometimes 4 to 12 weeks for full effect, though some people notice changes sooner.

Common side effects to watch for include injection site reactions, increased susceptibility to infections, and fatigue. Given your pregnancy, any signs of infection should be reported to your doctor promptly.

Since you're high-risk, close monitoring by both your rheumatologist and obstetric team is really important right now. Don't hesitate to reach out to them with any concerns as you start this new medication. 💛

June 1

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