myRAteam

Curious about whether marijuana or cannabis could help with RA? It's a topic that comes up often, and here's what's currently known.

Cannabis contains compounds like CBD (cannabidiol) and THC. These interact with the body's endocannabinoid system, which plays a role in regulating pain, inflammation, and immune responses — Show Full Answer

Curious about whether marijuana or cannabis could help with RA? It's a topic that comes up often, and here's what's currently known.

Cannabis contains compounds like CBD (cannabidiol) and THC. These interact with the body's endocannabinoid system, which plays a role in regulating pain, inflammation, and immune responses — all relevant to RA. Some early research, mostly in animal studies, suggests cannabis-based treatments may help reduce inflammation and slow joint damage. One small human study using an oral spray called Sativex (containing both CBD and THC) showed promising pain relief and reduced disease activity — but the study was small, and Sativex isn't approved in the U.S.

Two clinical trials are currently underway studying cannabis for pain and inflammation in people with RA, so more answers are on the way. Experiences among myRAteam members are mixed:

- Some report relief using CBD oil, tinctures, or topical lotions
- Others have tried CBD products and felt little to no benefit
- Results seem to vary quite a bit from person to person There are some important cautions to keep in mind. Cannabis and CBD can interact with common RA medications, including:

- Corticosteroids like prednisone
- NSAIDs like naproxen or celecoxib
- Xeljanz (tofacitinib)

These interactions could make RA treatments less effective or even be dangerous. Always speak with your rheumatologist before adding cannabis or CBD to your routine — they can help weigh the potential benefits against the risks for your specific situation.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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