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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 7, 2025
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For people with RA who are taking biologics or methotrexate, it's important to coordinate the timing of vaccines with your rheumatologist. Since biologics and methotrexate affect your immune system, proper timing of medication holds can help ensure the vaccines are most effective while maintaining your RA treatment plan.

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For people with RA who are taking biologics or methotrexate, it's important to coordinate the timing of vaccines with your rheumatologist. Since biologics and methotrexate affect your immune system, proper timing of medication holds can help ensure the vaccines are most effective while maintaining your RA treatment plan.

Key recommendations:
- Discuss your vaccination schedule with both your rheumatologist and primary care doctor
- Get all recommended vaccinations to prevent infections while on immunosuppressive medications
- Follow your doctor's specific guidance on temporarily pausing medications around vaccine dates
- Report any concerning symptoms or side effects to your healthcare team After receiving vaccines, watch for signs of infection including:
- Fever or chills
- Muscle pain or unusual tingling
- Rash or skin reactions
- Stomach pain or diarrhea
- Changes in urination

Contact your doctor immediately if you experience any of these symptoms, as people taking biologics have an increased risk of infections and need to be monitored closely.

September 7, 2025
COVID-19 and Rheumatoid Arthritis (RA) Essential Updates Read more >

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