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A myRAteam Member asked a question 💭
Victoria, BC
July 24, 2025
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What causes weight gain with rheumatoid arthritis medications?

Several RA medications can contribute to weight changes. TNF inhibitor biologics like adalimumab, etanercept, and infliximab typically cause modest weight gain of 2-5 pounds on average. Corticosteroids like prednisone can lead to more significant weight gain Show Full Answer

What causes weight gain with rheumatoid arthritis medications?

Several RA medications can contribute to weight changes. TNF inhibitor biologics like adalimumab, etanercept, and infliximab typically cause modest weight gain of 2-5 pounds on average. Corticosteroids like prednisone can lead to more significant weight gain through increased appetite, food cravings, and fluid retention. What can you do to manage weight gain?

Here are some helpful strategies:
- Work with your doctor to find the right medication balance
- Maintain a balanced diet with fruits, vegetables and whole grains
- Stay physically active as your condition allows
- Consider working with a physical therapist or registered dietitian
- Track your weight changes when starting new medications

Remember that if a medication significantly improves your RA symptoms, some weight gain may be an acceptable trade-off for better quality of life.

July 24, 2025

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