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Does Anyone Know Of A Medicine For RA That Does Not Make You Feel Ill?

A myRAteam Member asked a question 💭
Roanoke, VA

Just can’t take the thought of methotrexate any more.

April 21, 2023
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Answer Summary

Members rallied around the question of finding an RA medication that doesn't cause illness like methotrexate, sharing that everyone responds... Read more

Members rallied around the question of finding an RA medication that doesn't cause illness like methotrexate, sharing that everyone responds differently to treatments and that trial and error is unfortunately part of the process. Several members described medications that worked better for them, including Rinvoq, Enbrel, Humira combined with lower-dose methotrexate, Simponi Aria infusions, Rituxan infusions, and sulfasalazine, with many noting that adding folic acid or adjusting dosages helped reduce side effects. A recurring theme was the importance of communicating openly with your rheumatologist, giving new medications a fair trial while knowing when to stop if side effects become unbearable, and holding onto hope that the right treatment combination exists even when the journey feels exhausting.

A myRAteam Member

I could not tolerate Methotrexate, others have no issue. We are all different and react differently to the drugs. Speak to your Rheumatologist, let them know you cannot take Methotrexate anymore. There are lots of other drugs you can try. Unfortunately, it is trial and error. Hope you find a drug you can tolerate and it works wonders for you. Wishing you well.

April 21, 2023
A myRAteam Member

Thank you all for your responses to my question about methotrexate. There’s a lot to think about and evaluate.

April 23, 2023
A myRAteam Member

KEEP TRYING MEDS. Many will be fine.

April 22, 2023
A myRAteam Member

My doctor order sulfasalazine & I’m up to 3 pills, twice a day with lots of water. My daughter has been on sulfasalazine (1tablet a day) for 6 years bcz she has Crohns. She’s had no problems with it either.

April 22, 2023
A myRAteam Member

Hi JuJu,

It was the same as Tiena for me. I couldn't take methotrexate. Keep trying different meds until you find the right medication for you. I'm now on Rituxan infusions which I tolerated better than all the other medications I tried.

April 22, 2023

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