I have been taking Gabapentin and it works well.😃

Leflunomide did nothing for me,just caused a lot of side effects,like rash, and brain fog. also had that reaction to metho,pill, have been on metho injection and no problems for the past 6 months.

I developed bouts of paresthesia and heart palpitations after taking leflunomide. Once I stopped taking the leflunomide, those symptoms waned and were completely gone after a few months. I'm back on a higher dose of methotrexate, although it doesn't help much with the joint pain.

I'm sorry you have RA and some of the many associated ailments. My brother does great on the methotrexate, but he often gets what he calls the "methotrexate hangover" and sleeps in for several hours. Methotrexate worked the best for my symptoms but after a year started causing liver issues. Been on Humira a year and a half. It doesn't work nearly as well for me. RA doc and I are trying to figure out my feet problems now. MRI of my left foot in two weeks. Hang in there!

I actually feel that muscle relaxers do a lot better for me then meds like Lyrica and those types of medications. I never had any relief from neuro meds. I use Zanaflex and that works so much better.