Answer Summary

Members shared deeply personal experiences with methotrexate for rheumatoid arthritis, with many calling it a miracle drug that significantly... Read more

Members shared deeply personal experiences with methotrexate for rheumatoid arthritis, with many calling it a miracle drug that significantly reduced pain and swelling, particularly when paired with daily folic acid to prevent side effects like nausea and hair loss. Several members reported success with both pill and injection forms, noting that injections often work better for those with stomach issues, while others described challenges including persistent fatigue, hair thinning, and rare cases where the medication simply didn't work or caused adverse reactions that required switching to biologics like Humira, Enbrel, or Xeljanz. A recurring theme was the importance of patience, as methotrexate can take several months to show improvement, open communication with your rheumatologist about any concerns, and the reassurance that it's normal to try different medications until you find what works best for your body.