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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does Anyones ALT Liver Enzymes Go Up Whilst On Methotrexate X

Does Anyones ALT Liver Enzymes Go Up Whilst On Methotrexate X

posted November 21
A myRAteam Member

Yes MTX can elevate. But even 1 drink will raise them; so if you drink, try to avoid alcohol a few days before blood draw. I try to avoid any alcohol in general because of this. When I do drink it's maybe a glass of wine or a beer tops. My doc told me if the alt or other are more than double the max limit, to suspend MTX until they drop back down. Hope that helps.

posted 3 days ago
A myRAteam Member

Yes that is what is happening with me too but they have referred me for a scan now

posted November 23
A myRAteam Member

Yes my Dr said after blood tests this happened. The surgery kept making a big fuss about it, but my consultant wasn't that bothered.

posted November 22
A myRAteam Member

They have been going up and down this time it was ALT 50 x sorry to hear you have had this problem too x

posted November 21
A myRAteam Member

Hi Annkirsty,

Yes, my liver enzymes elevated with methotrexate and Humira. My doctor emailed me and stated we'll keep an eye on the liver. I stopped both medications. I start an infusion medication in December.

My thoughts always return to the fact we're trying to treat one illness and the medications can damage other organs. I

Were your liver enzymes mildly elevated or higher?

posted November 21

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