Anything or nothing can happen. Some erosion is just life and aging. Don't worry until your fingers hurt, knuckles or joints too large or cysts form. I have had one hand grafted and in Nov my ring finger will have a k wire inserted to fuse it. That's the other end of the spectrum but you may never walk that pathway. Prayers for you.

Hi Butters and welcome:-) I took one dose of methotrexate and I was so very sick it was like death. Rhuemy pulled me off right away and put me on Arava instead and that was way better. It’s like getting the right cocktail to help. I’m still in that boat, but when I look at where I am now compared to a year or even two years ago I’ve noticed a difference. Just not so sure if it’s enough. Scary isn’t it? This disease is like a pinball machine! And turns you into a human barometer. My son asks if I feel it will rain and if he needs to roll up his windows! I couldn’t help but laugh! Ha! But, in all seriousness the weather any change effects me. Stay strong and reach out anytime! I’ve added you to my team🤗❤️

Hi, I am also negative on everything as well just like you. I do have seronegative ra. All my levels have been low but the swelling and symptoms are apparent. My mom started out the same way and ended up sero positive later down the road. Hang in there, this is an amazing support to have on this site and I hope you get some relief soon.

Ok thanks Dawnmichelle. I will sit out these first few months while it kicks in and see. Thanks for your help ❤️

Hi 🙋🏻‍♀️ me too. Negative on all but the CRP. I am very low on B12 now too. I’m also new, also a bit in denial. This is my 4th week on Methotrexate and I hate it. I know I have to wait a few months for it to work, but I now get headaches, feel nauseous all the time and have no energy. I have started monthly B12 injections and have a Vitamin D oral spray daily. I am off work with PTSD, Agoraphobia, Panic Disorder and Anxiety- so this diagnosis is a big disappointment. But, I am grateful to know why my hands hurt, knees, elbows, feet. I bought the compression gloves and like them. I have Skin Picking Disorder too - which is just an extension of all the anxiety stuff. But the gloves help me not focus as much on keeping my hands straight at night. Even if they are a placebo, it feels like they are supporting me mentally. Everyone is saying to exercise, but I feel so sick on the medication 24/7. Hoping it gets better. Thanks for your share