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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Brain Fog & Methotrexate

Brain Fog & Methotrexate

After reading everyone’s responses to brain fog, I’m wondering if I should ask my rheumatologist to place my Methotrexate on hold. I’ve been on it for several years. Has anyone noticed any changes in your health & brain fog, etc.?

Thanks for your comments.

A myRAteam Member said:

For me brain fog is either me fighting an infection or issues with gut bacteria (doing research). If I get pneumonia or other infection my brain totally falls out the window.

posted 9 days ago
A myRAteam Member said:

I attribute my brain fog to severe, long term chronic insomnia. Lack of sleep is very brain damaging. I can't even remember when I last got more than 4 hrs of sleep, but it is usually less.

posted 12 days ago
A myRAteam Member said:

I’ve been taking mtx for about a year now. It’s only been a couple of months that I’ve started having the brain fog experience. It was pretty random until around 6 weeks ago. I think it has something to do with the low oxygen levels from getting sick

posted 14 days ago
A myRAteam Member said:

H2, that’s when my “brain fog “ was the worst. I caught covid then bacterial pneumonia. Oxygen levels went really low. Pulsox showed 87 and would not budge. Then I went to er and was admitted, blood clot in my lung…

posted 9 days ago
A myRAteam Member said:

The fog is more RA not the meds. If I take benadryl or anything to help me sleep- I wake up stupid... Well, more stupid. Part of it may be ageing and just getting my circulation going. Or neurons sparking like an engine misfiring in the cold weather. Coffee does help!

posted 10 days ago
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