There really isn't a best medicine. We all react differently to RA meds. Enbrel is the best for me.
I’m taking planquenil and RINVOQ now. I’ve tried Enbrel, Xeljanz, methotrexate, Humira, diclofenac in less than a two year period due to having fibromyalgia that made injectables impossible to take. I find the Planquenil a very underrated drug. It, combined with the RINVOQ, works well, especially for severe RA.
I don't get side effects anymore. When I first took it, I got headaches mainly. It went away after about 3-6 months.
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