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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone Had Issues With Methotrexate & Humari Causing Fever Blisters & Mouth Sores

A myRAteam Member asked a question 💭
Hayes, VA

Three weeks ago started Methotrexate again and I was already on Humari. This weekend I developed a Fever Blister and mouth sores. I am just curious if anyone else has experienced. Possibly Im trying to fight off a virus or something.

Any input would be appreciated.

April 3, 2022
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View reactions
A myRAteam Member

I would add some L-Lysine. It's a supplement that you can get at Walmart. Helps with coldsores too.

April 6, 2022
A myRAteam Member

I used to get mouth sores from MTX. A friend suggested increasing daily folic acid and switching to regular ("old-school") Crest toothpaste. No sores - 4 months and counting. Hope you'll find what works for you soon ...

April 5, 2022
A myRAteam Member

I've been on Methotrexate for 10 months. My doc started me on Folic Acid at the same time(like Marjorie). I only had a week of stomach distress but have been okay with the medication.

April 5, 2022
A myRAteam Member

My doc prescribed folic acid for the mouth sores....try loading up on folic acid

April 4, 2022
A myRAteam Member

I was not able to tolerate MTX at. all. Good luck!

April 3, 2022

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