Answer Summary

Members responded to concerns about severe headaches while on biologic medications, with many sharing that headaches are a common side effect... Read more

Members responded to concerns about severe headaches while on biologic medications, with many sharing that headaches are a common side effect they have experienced across multiple treatments including Orencia, Humira, Actemra, and Xeljanz. Several members described how headaches can be directly related to both RA itself and environmental factors like air pressure and humidity, with one member's neurologist confirming this connection and another being advised to see a neurologist for preventative medication if headaches continued. A recurring theme was the challenging balancing act between managing RA symptoms and tolerating medication side effects, with members offering practical relief strategies like warm compresses, rest, staying hydrated, and in some cases finding success with Enbrel when other biologics failed.