I take leflunomide 20 mg have been on it almsot a year, i also take enbrel. I love leflunomide its always been my “back burner medicine” it has always stayed constant as i have tried methotrexate, humira and now enbrel (which seems to be my perfect combination-enbrel and leflunomide) the only side effects i had initially was headaches and they were terrible but after a few weeks stopped completely! I really do believe in this medication! Good luck!