Answer Summary

Members shared their preferred injection sites for methotrexate, with most choosing fatty areas near the belly button or on the thigh. Several... Read more

Members shared their preferred injection sites for methotrexate, with most choosing fatty areas near the belly button or on the thigh. Several members described the stomach as less painful and easier to tolerate, with no bruising or bleeding, while others found the thigh more comfortable and less painful, though one member compared thigh injections to feeling like a gunshot. A recurring theme was that personal preference matters most, as everyone's body responds differently to needle placement in various areas.