Answer Summary

Members shared mixed experiences with sulfasalazine for rheumatoid arthritis, with some finding it effective when paired with medications like... Read more

Members shared mixed experiences with sulfasalazine for rheumatoid arthritis, with some finding it effective when paired with medications like Celebrex or celecoxib for added relief, while others reported it stopped working after a few years or caused challenging side effects like nausea and low white blood cell counts. Several members offered practical advice, including taking the medication after meals to reduce nausea, splitting doses throughout the day instead of taking them all at once, and being patient as it can take time to see results. A recurring theme was the importance of open communication with doctors about what is and isn't working, as many members eventually needed to adjust their treatment plan or add a biologic when sulfasalazine alone was no longer enough.