Answer Summary

Members offered guidance to someone who developed a fever and flu-like symptoms shortly after starting methotrexate, with the strong consensus... Read more

Members offered guidance to someone who developed a fever and flu-like symptoms shortly after starting methotrexate, with the strong consensus being to contact a doctor immediately and not take the next dose until cleared by medical staff, as infections while on this medication require prompt attention. Several members shared that their doctors instructed them to stop methotrexate whenever they got sick and resume only after recovering, while others mentioned common side effects like hoarseness, sore throat, and stomach issues that improved with adjustments like splitting the dose or drinking plenty of water. A recurring theme was frustration with the original poster's doctor not returning urgent calls, leading many to urge an ER visit if symptoms worsened, with relief expressed when the doctor finally responded, apologized for the communication breakdown, and temporarily stopped the medication until an infection could be ruled out.