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A myRAteam Member asked a question 💭
Queensland

Hello everyone,

My rheumatologist has advised that I move off my methotrexate/plaquinil/sulfasalazine combo and change to Simponi injections, once per month.

Can anyone advise me what to expect when using this drug please?

Do I still need to avoid alcohol and sun exposure?

Should I still take folic acid?

Apparently, I will be instructed on its use once funding is agreed.

I was told very little about this medication except it is very expensive and can work well for some people.

Thanks for… read more

July 4, 2019
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Answer Summary

Members shared mixed experiences with Simponi for rheumatoid arthritis, with some noticing immediate relief while others experienced severe... Read more

Members shared mixed experiences with Simponi for rheumatoid arthritis, with some noticing immediate relief while others experienced severe headaches or no pain relief even after months of treatment. Several members emphasized that biologics work differently for each person, with timelines varying widely, and many recommended giving the medication adequate time to build up in the system while staying in close contact with their rheumatologist about side effects. A recurring theme was the importance of patience and persistence in finding the right treatment combination, with members offering encouragement to stay hopeful and reminding each other that this community understands the physical and emotional challenges of living with RA.

A myRAteam Member

I've been on Simponi for 4 years. It has helped me a lot more than any of the other biologics. I am not taking folic acid. I do take hydroxychloriquine. The doctor will give you instructions once your insurance approves. I do Simponi infusions every eight weeks. There is an assistance program to help with cost if you qualify (ask your doctor about it). I like Simponi a lot. I hope it helps you.

July 6, 2019
A myRAteam Member

I agree MarciaBiller, I also take folic acid, methotrexate and plaquenil, along with Humira. My labs have been good as well. Still have some pain, but also have osteoarthritis in both hips and one knee. So I do think it depends what other factors play into it.

July 17, 2019
A myRAteam Member

My doctor insisted a take folic acid with Methotrexate. I also take plaqlinil (spelling) and so far my labs are good. I guess medications depends on any other medical problems we may have or each person reacts differently.

July 16, 2019
A myRAteam Member

Thanks everyone for your very helpful replies. I am still waiting for approval for my new meds.

Unfortunately my rheumatologist is a four hour drive so I don’t see her that often.

I will be having a Skype appointment with her when I start my new medication.

At least I now have an insight of what to expect (or not) I suppose I have been pinning my hopes on this being the answer, now I will be more prepared in case it does not work for me.

Best wishes everyone in your own endeavours to best this thing.

Cherry

July 14, 2019
A myRAteam Member

I have been taking simponi for the last 2 months and I have had no side effects but to be honest with you I have had no pain relief either so I don't think it's quite working yet. I have been told that it can work very fast for some people so stay optimistic!

July 4, 2019

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