I have been taking Humira since last fall. It takes time for the drug to work, but I couldn't be happier-- very good results. Way less fatigue, way less pain. My husband has noticed how much more energy I have. And my rheumy said at the next visit we can discuss tapering down the Methotrexate and Plaquenil. There is no sting on injection at all (citrate-free Humira).

All I can say is we are all different. My pain after years has driven me to humaira. It was not the solution for me I will start infusions and again when pains are so bad you will try it. Yes it's scary but staying in a world of pain and in bed is scarier.
Be aware not anxious and see how ya do. Generally allow 8 to 12 weeks to see how ya do and let it get in there. If not improved by say 4 to 6 weeks somewhat tell your Dr. And move on . Good luck to you.

Thank you all for your responses so appreciated. I just found out I have thyroid modules. From what the doc said there are several and some r quite large. I’m waiting for an appointment to get a biopsy. This has put the humera on hold. Anyone experience thyroid issues? Not sure now if I will /do want to take it knowing I have this and the cancer risk of the drug. A lot of decisions.

At the moment I am avoiding biologics due to having melanoma and currently dealing with basal cell carcinoma. I endured major bowel problems last night after eating a taco salad. Dr. found polyp during my first colonoscopy so now I have one every 5 years. Turned 71 this January.

Hard call. A personal one.i would see see if MTX works with occasional predisone if needed . I have done injections and infusions they state infusions do not cause blood clots . Orencia. Shots some can cause clots . Goal get a full check from cardiologist and go to a hematologist to ensure proper clotting . Not one Rhuematologist does this . Mine is proactive and did not do this. Mind you shots didn't work for me . Nor 4 months of infusions you maybe different. I ended up with bi lateral pulmonary embolism. I also now a small ascending aortic aneurysm about 4.3 . So we watch it. Listen to your body . That is the biggest advice I can give. Keep us posted and enjoy your day.
Joan