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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I Had My Second Systemic Prednisone Injection 3 Weeks Ago And Did Not Get Relief In My Joints This Time. I Iam So Discouraged!

A myRAteam Member asked a question 💭
Guelph, ON

First time provided relief and improved mobility.
Been in an active and worsening flare for several years. Have RA and lupus with a large number of active joints. Was able to get relief to my colon symptoms both times but not my joints second time. I don't understand why and it's so frustrating!

February 4, 2019
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A myRAteam Member

It's so true! I heard once that you can count on gaining roughly a pound per mg of your doseage. It's literally a lifesaving drug, but also, who needs the extra weight on painful joints?!!

February 7, 2019
myRAteam

I'm sorry to hear that you're feeling discouraged. Here are a few points to consider:

- Effectiveness: Sometimes, the effectiveness of treatments like prednisone can vary. It's possible that this particular injection didn't work as well as previous ones
- Consult Your Doctor: It's important to discuss this with your Show Full Answer

I'm sorry to hear that you're feeling discouraged. Here are a few points to consider:

- Effectiveness: Sometimes, the effectiveness of treatments like prednisone can vary. It's possible that this particular injection didn't work as well as previous ones.
- Consult Your Doctor: It's important to discuss this with your doctor. They might suggest adjusting your treatment plan or exploring other options.
- Side Effects: Remember that prednisone can have side effects, so it's crucial to use the lowest effective dose and not stop suddenly without medical advice.

Stay hopeful and keep communicating with your healthcare team!

July 7, 2024
A myRAteam Member

Weight gain with terrible l went 165 to around 200. Doctor and I said no more lost most of it

February 7, 2019
A myRAteam Member

Lynnie, 60 mg per day is a lot of prednisone!! I think I was taking a much lower dose.... maybe 5 mg a day while I was pregnant. I am glad I have prednisone on hand for flare-ups, but the weight gain (especially during pregnancy) was horrible! I went from 100 lbs to Mrs. Santa Claus. And Baby 3 weighed more than babies 1 and 2. The 5-day treatment works for me; I actually had to do it in January when I had a hip flare-up and walking was difficult. Each pill is 1-mg, so I'm taking 5 mg the first day, and weaning by 1 mg a day.... so it's a 5-day treatment. With a 5-day treatment, I don't have the weight gain to worry about. I've never tried Cymbalta. I'll be praying that you find something that works with minimum side-effects.

February 6, 2019
A myRAteam Member

Also, I have recently started cymbalta as well. I'm hoping it helps. Do you find it works?

February 6, 2019

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