Yes, until your body regulates it

Biologics are medications used to treat RA. I'm sure you've see the ads on TV for Humira and Enbrel. They are sometimes necessary to take in addition to methotrexate to treat the RA

Yes! I take it Saturday morning and by Wednesday I start to feel fatigue and pain again. Once I take it on Saturday it feels like it takes a day to get in my system again. Will talk to my doc about increasing the dosage...

Fell well soon!

The trexate is working... Yes, sometimes it slows down. It takes two weeks to flow out of your system. I have to take mine weekly as well and I find that by Wed, I'm ready for my Friday dosage.
How do you use prednisone for so long? It messes with my muscle functions...especially my bladder and kidneys? My doctors took me off after two weeks!!

Hi all. I used to be a blood donor but am unable to donate once taking methotraxate. I was advised I could start donating again three months after I stopped taking methotraxate. So it remains in your system for awhile