I take methotrexate (orally) on Friday nights. From Saturday to Wednesday, the pain is a lot less. I can also go down to 15mg of prednisone. By Wednesday night, I can already feel a difference and I need to go back up to 20mg of prednisone on Thursday morning or else I wouldn’t be able to put any weight on my foot. Is it possible that the methotrexate is wearing off?
Yes, until your body regulates it
Yes! I take it Saturday morning and by Wednesday I start to feel fatigue and pain again. Once I take it on Saturday it feels like it takes a day to get in my system again. Will talk to my doc about increasing the dosage...
Fell well soon!
The trexate is working... Yes, sometimes it slows down. It takes two weeks to flow out of your system. I have to take mine weekly as well and I find that by Wed, I'm ready for my Friday dosage.
How do you use prednisone for so long? It messes with my muscle functions...especially my bladder and kidneys? My doctors took me off after two weeks!!
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