Sheri, I don't know if you remember, but I had one lone injection of Humira. It seemed to help, even overnight! However, it turned out I was allergic to it. Had itching and eventually, could feel it in my throat and tongue. It was too dangerous for me to try another injection so switched to Enbrel. I have seen nothing good while on the Enbrel and hope to be switched again in January.

I had some success with it for about 9 months, then failed. That has been a common pattern for me with all of the tnf inhibitors. Drugs with a different mechanism of action, like Actemra are a good thing to try if you don't get results with Humira. Best wishes for successful treatment.

Hi- I was on humira for about 7 years- it was a blessing for me - downside- I ended up with a rare side effect- demylinating and mimicking ms- not good- can never go on that type biological again- I will stress that you look at all the possible side effects on anything you go on and make sure you tell your Rheumatologist when anything comes up- and stress this as I was poppies so it took months to get to the point I could not hardly function- just want to make sure everyone gets this! Good luck!!

I have been on a lot of different medication combinations. None of them worked really well. The last combination was methotrexate and humira. After four injections I broke out in hives all over my body. So now I will be trying orentia. Humira is a great drug but like anything else it can cause allergic reactions. Good luck and hugs.