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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myRAteam Member asked a question 💭
Lebanon, TN

I am on MTX 10mg pills once a week. Tomorrow night is my next MTX dose. I have had nausea all week to some extent. Is this from the MTX, a part of RA, or just my body dealing with the stress of this new diagnosis? Have you experienced it? If so, what do you
do?

June 28, 2017
 · 
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Answer Summary

Members shared their experiences with methotrexate-related nausea, confirming it's a common side effect of the medication rather than RA... Read more

Members shared their experiences with methotrexate-related nausea, confirming it's a common side effect of the medication rather than RA itself, with many describing feeling sick for 24-48 hours after their weekly dose. Several members offered practical strategies that helped them, including taking the medication in the morning with food instead of at night, switching from pills to injections (which many found caused less nausea), drinking ginger tea or peppermint oil, staying well-hydrated, keeping food in the stomach throughout the day, and taking prescription folic acid or anti-nausea medications like Ondansetron. A recurring theme was the importance of communicating with your rheumatologist about persistent side effects, as adjustments to dosing method, timing, or medication type can often provide significant relief.

A myRAteam Member

I got sick when I first started my mtx. My Dr have me a rx for phenergan. But I used a tried and true remedy that has been passed thru my family and it really helped. Ginger tea. You can either get fresh ginger root, cut and shave off about a TBSP into about 16 oz of cold water in a pot on the stove. Put it on med high heat for about 10 to 12 minutes. Don't let it boil, keep it at a simmer. If it's too bitter, sweeten with some honey, not sugar. A lot of health food stores carry ginger tea as well, but it doesn't work as well and it has more chemicals in it. I hope this helps you!

July 3, 2017
A myRAteam Member

Max can cause nausea. If the pills continue to bother you, ask your doctor if you can have the shots instead. They bypass the GI tract and don't cause as much nausea.

July 8, 2017
A myRAteam Member

More than likely it's from the methotrexate. Let your rheumy know you are experiencing these side effects. It's possible you might need to change to the injectable kind. You should also be taking a prescription folic acid.

June 28, 2017
A myRAteam Member

its from the methotrexate, same thing happened to me

June 30, 2017
A myRAteam Member

Just had my second dose today and your suggestions made it much easier. Thanks!

June 29, 2017

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