I plan on asking my RA doctor in Nov. about stopping Methotrexate...last visit was with the PA and she definitely did not want me to stop..said the biologics work better while staying on the Methotrexate. I plan on doing some more reading up on what the research studies have shown..

Since methotrexate at 10.5mg tablets didn't work for me, my doctor said one option was to up the dose and the other option was to try a new medication. I decided to up the dose one more time. If that doesn't help she said we will move to something else. Honestly, and this is just my paranoid opinion, I think that some doctors get spiffs or bonuses from certain pharmaceutical companies to promote their products. I'm pretty picky about my doctors and got really lucky with one that I truly trust to have my interests in mind, not just hers.

Hi
I was on 2 mtx per week and my body thought it was packing in :( worst time of my life and to be honest since I stopped (6/7 weeks ago) I'm not noticing any big change in my hands, they hurt a little but they did that on mtx, my mind is at ease, my hair stopped falling out and I feel back on track :) I stopped the mtx myself as I had told my rheumy who said I need to keep taking it but it was after that appointment that everything got worse and I couldn't get back in to see him so I gradually took myself off it, I realised that I know me and my body and I need to take more control over it as I really was in a bad place and knew it was the mtx but the rheumy refused it :( anyway I'm seeing every day that I have minimal and very manageable pain a bonus and I am making the most of it :) good luck to you and I hope you get things sorted :)

im new here so excuse me for maybe placing my material comments wrong places