My flares always start with feeling fatigue and my hands and feet hurt and from there my hips. About enbrel, it worked well for me while I was on. Just irritation at injection site. One thing is to inject in the stomach it is not as painful as on the arm or hip. Good luck to you. By the way it just stopped working and that's why I'm not on it anymore.

Some flares are so very painful and you have pain everywhere. Believe me you will know when you are in a bad flare, and then there are some that are not do bad, and they pass quickly. My first bad flare I couldn't even lift my head and I did not know what was happening to me. Having a flare is definitely a powerful experience. Unfortunately for us.
Blessings to you and yours

@A myRAteam Member it just depends on the person and the medication. Everything I've tried only worked max 9 months except rituxan which is what I'm on now. I pray it keeps on working because I'm running out of meds to try. I hope this helps.

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A myRAtea...

I am adding to my earlier post. I just started Enbrel. I had a 2 week break between Humira and Enbrel due to waiting for insurance. The night of Day 5 after taking the injection of Enbrel I had a headache. Woke up with it on Day 6 and it continued the entire day and night and my joints starting hurting just a bit. Day 7 the headache was throbbing when I woke up and I was still hurting and my joints were swollen but I still made it to exercise class then came home around noon and did my injection I continued to get worse the rest of the day and by dinner time I felt like I got hit by a semi. My daughter kept calling my name every 5 minutes because I couldn't stay awake longer then a few minutes. I had never been that bad so I thought okay this is a flare. My thumbs were so swollen and I could barely move them. When I fell asleep for the night and woke up in the morning I was 80% better. Headache was gone and I only ached from hurting the day before. I don't know if you call that a flare or the medicine wearing off about 36 hours early. I hope my body adjusts to the medicine because I can't go through though that every week. I am on Day 4 of the second injection and my thumbs today got huge again and I can't bend them and the arches of my feet hurt and my ankles hurt just to push the gas peddle. I don't know if it's the weather or if this is called a flare or my body just needs to adjust. It is all just so confusing!! I'll update as the weeks go by.

Never been on Embrel but have been on Humira or about a year ans=d it works and all is good!!!