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Real members of myRAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does Anyone Know How Long You Should Be Off Antibiotics Before Resuming RD Meds?

A myRAteam Member asked a question 💭
Lincoln, DE

Biologic and methotrexate

January 18, 2016 (edited)
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Answer Summary

Members shared varied experiences about how long to wait after finishing antibiotics before restarting RA medications, with the most common... Read more

Members shared varied experiences about how long to wait after finishing antibiotics before restarting RA medications, with the most common recommendation being seven to ten days, though some members reported timelines ranging from just two days to a full month depending on their doctor's preference and the specific medication. Several members emphasized the importance of consulting with a rheumatologist or pharmacist, as different antibiotics have different half-lives and some medications like Arava may not need to be stopped at all. A recurring theme was ensuring the infection is completely cleared before resuming immunosuppressive RA treatments, with many members noting their doctors closely monitor the restart timeline to balance infection risk with disease management.

A myRAteam Member

The infection/disease needs to be cleared up; and you need to be off antibiotics completely before resuming your RA meds. If you're still in doubt, ask your rheumy.

January 21, 2016
A myRAteam Member

A week

January 19, 2016
A myRAteam Member

Usually a week

January 19, 2016
A myRAteam Member

Ask your pharmacist. They are the ones who gave my doc the facts. You can take cephlacore (omniceph) with methotrexate. It depends on the antibiotic...how long it stays in your system.

January 18, 2016 (edited)
A myRAteam Member

about 1 month. but call your r.a. doctor. when you fell much better than you go back on methotextrate. stay away from people who has a cold or flu. this medication does weaken your immune system down. I am on this medication over 1 1/2 year and have been sick and had to be taken off this medication for about one month or so.

January 25, 2016

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