I was like @A myRAteam Member. Originally I was injecting methotrexate once a week. I would get a glimpse of the vile out of the corner of my eye and would become nauseous. The drug itself made me feel sick and very fatigued. I didn't experience any pain with it though. I've since been switched to Arava with no side effects.

Mentioned Users

A myRAtea...

I cannot tolerate mxt at all. Made me very sick but also seemed to make my R.A. worse. Had a lot of joint pain for few days every time I took it. It is a powerful strange med.

I too had unpleasant experiences with the oral medication and moved on to the injection. I have one day of a bit of fatigue now but all the nausea and other discomfort is gone.

I got up to taking 10 pills a day..I was so sick allday everyday but the injection is once a week and although I see a few side effects it works better and I dont feels as sick.

It got so bad that just thinking about taking it made me feel sick.....