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A myRAteam Member asked a question 💭
Omaha, NE

I'm on methotrexate and got my flu shot on Tuesday and have had fevers up to 102.6 off and on since then. I was told to go to the ER on Wednesday, and they said my body was tricking itself into thinking it had the flu due to my suppressed immune system. Has anyone else experienced this? Today is the first day I've gone without Tylenol, and I thought I was doing better, but had a temp of 101.5. The doctor said I wasn't contagious, but I'd like to know when this will pass! Thanks!

October 23, 2015 (edited)
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Answer Summary

Members shared varied reactions to the flu vaccine while on methotrexate, with most reporting no issues and one describing a severe multi-day... Read more

Members shared varied reactions to the flu vaccine while on methotrexate, with most reporting no issues and one describing a severe multi-day fever similar to the poster's experience. Several members offered practical guidance, including alternating Tylenol and ibuprofen to manage fever, staying hydrated, using ice packs wrapped in towels, and following up with a doctor if symptoms persist beyond three days or worsen. A recurring theme was confusion around which vaccines are safe on immunosuppressants, with members asking about the shingles vaccine and sharing conflicting advice they had received from their doctors.

A myRAteam Member

i was told the shingles shot was a live vaccine and not to take it but the flu and pnuemonia shot was ok

October 29, 2015
A myRAteam Member

Gabreal, my rheumatologist also strongly recommended it, along with the pneumonia and shingles vaccines. I also work for a hospital system that requires (and provides) the flu vaccine unless you have a good reason not to get it. I still have a low grade fever off and on and a cough, but am feeling better overall. Thank you!

October 25, 2015
A myRAteam Member

I don't get the flu shot, mainly because I don't get sick. The last time I had the flu was well over ten years ago. Even with my immune system depressed, I still don't get sick.

October 25, 2015
A myRAteam Member

Can I take the shingles vaccine along with the methotrexate and folic acid? I have been holding off taking the meth and folic as I heard you couldn't take both together. Does anyone know? Seeing my Rheumi tomorrow morn.

November 22, 2015 (edited)
A myRAteam Member

With a suppressed immune system it could last over a week. I was told to get the shot since it is a dead virus. I am due in September. I have to take the shot because I am an RN and work in the hospital. The fever is actually a good thing. Viruses can't tolerate temps of 100 or higher. Just keep the fever under 101 if possible because you will be miserable if it gets much over that. Just keep drinking fluids and rest as much as possible, much like having the flu. Your body will build antibodies during this time and if you are exposed to the flu later, it should be a much milder case. If your temperature keeps rising, try alternating Tylenol (Acetomenophen) and Motrin (Ibuprofen). You can take each of them 4 hours apart. Try taking one then the other 2 hours later if your temp is high. Obviously, if your temp is under control, don't take the meds as often. Just be sure to stay under 4 grams of Tylenol in a 24 hour period. More than that can cause permanent liver damage. Of course, if you are still having problems, call your doctor. He may have other suggestions. Ice packs around your neck, wrists and groin area will also bring down your temp, but be sure to wrap them in a towel to keep the ice from damaging the skin.

July 29, 2016

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A myRAteam Member asked a question 💭
Cleveland, OH

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