Are you taking folic acid with the Methotrexate. I had problems off and on first few weeks then it settled down. How often do our take an injection if you use that method?
are you on oral Methotrexate? I am on injection and no gastric problems.
I had horrible trouble with both Plaquenil and Methotrexate. I'm nearly 4 months on Humira (shots) and no gastric problems, much fewer migraines, and I'm actually seeing dramatic improvement when it comes to fatigue. Although, "pain fog" still is a problem so far.
I did too on the tablets but much better on the injections